Ruger Mark IV 22/45
The Ruger Mark IV 22/45 is the 1911-grip-angle variant of Ruger’s legendary Mark IV .22 LR target pistol — using a polymer grip frame angled at the same 18-degree grip angle as a 1911, rather than the Mark IV Standard’s steeper Luger-style angle. For 1911 shooters who want a .22 LR trainer that matches their carry gun’s grip angle, the 22/45 provides that platform consistency. Available in Standard, Lite (aluminum upper), and Tactical (threaded barrel) configurations.
Read our full Ruger Mark IV 22/45 Buying Guide ↓
22/45 vs. Standard Mark IV: Grip Angle Is the Difference
The standard Ruger Mark IV uses an aluminum grip frame with a steep, Luger-style grip angle. The 22/45 uses a polymer grip frame molded at the 1911’s 18-degree angle. If you shoot a 1911, Sig P226, or Browning Hi-Power, the 22/45’s grip angle will feel natural. If you shoot Glocks or other striker-fired pistols, the standard Mark IV or the 22/45 are both viable — try both angles and see which points naturally for you.
22/45 Lite: The Lightweight Option
The 22/45 Lite uses a ventilated aluminum upper receiver instead of steel, cutting weight to approximately 25 ounces. The Lite’s lighter weight makes it more comfortable for extended range sessions and steel-challenge competition where you’re holding the pistol up for extended periods. Available with threaded barrels in multiple finishes and barrel lengths.
22/45 Tactical: Suppressor-Ready
The 22/45 Tactical ships with a 4.4-inch threaded barrel (1/2x28) and a Picatinny rail under the barrel for a weapon light. Pair with a .22 LR suppressor and subsonic ammunition for one of the quietest, most enjoyable suppressed shooting setups available. The threaded 22/45 is one of the most popular .22 LR suppressor hosts on the market.
One-Button Takedown
All Mark IV variants (including the 22/45) use Ruger’s one-button takedown system — push a single recessed button on the back of the frame and the upper lifts off the lower for cleaning. This is a massive improvement over the notoriously difficult Mark II and Mark III takedown procedure and makes the Mark IV the easiest .22 LR pistol to clean and maintain.
22/45 for Competition
The Mark IV 22/45 is a popular platform for Steel Challenge, Rimfire Challenge, and NRA Bullseye competition. The 1911 grip angle gives consistent presentation for shooters who also compete with 1911-pattern centerfire pistols. The Lite and Competition models with their longer sight radius and lighter weight are the most popular competition variants. Volquartsen makes extensive aftermarket parts (triggers, barrels, compensators) for the Mark IV platform.
Frequently Asked Questions
What’s the difference between the Mark IV and Mark IV 22/45?
Grip angle. The 22/45 uses a 1911-style polymer grip frame; the standard Mark IV uses an aluminum grip frame with a steeper angle.
Can I suppress the 22/45?
The Tactical model ships with a threaded barrel ready for any .22 LR suppressor. The Lite models are also available with threaded barrels.
Does the 22/45 use the same magazines as the standard Mark IV?
Yes — all Mark IV variants share the same 10-round magazine.
22/45 Lite vs. 22/45 Tactical?
Lite for lightest weight (aluminum upper). Tactical for suppressor use (threaded barrel + rail). Both are available with threaded barrels in some configurations.
See Also: Ruger Mark IV • Ruger • .22 Pistols • Volquartsen • .22 LR Ammo • Suppressors • Competition Guns